Progestogen-anti-progestogen regimens
AssigneeAkzo Nobel N.V.
InventorsHerman Jan Tijmen Coelingh Bennink, Pieter M. Verbost
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Abstract
Disclosed is a contraceptive and/or HRT (hormone replacement therapy) kit comprising sequential daily dosage units each containing as the sole contraceptively effective ingredient of a progestogen, or as effective ingredient for HRT a progestogen with or without an estrogen or an estrogen only, and further two or more dosage units comprising an anti-progestogen. One of the anti-progestogen is administered at the beginning and the others regularly divided throughout the cycle, preferably one only in the middle of the cycle.
Claims11
A contraceptive and/or HRT (hormone replacement therapy) kit comprising sequential daily dosage units each containing as the sole contraceptively effective ingredient a progestogen, or as effective ingredient for HRT a progestogen with or without an estrogen or an estrogen only, and further two dosage units comprising an anti-progestogen.
A contraceptive and/or HRT kit 1 consisting of four to eight phases in which the odd-numbered phases all comprise a single dosage unit containing an anti-progestogen and optionally a progestogen and the even-numbered phases all consist of 8-15 dosage units containing progestogen, estrogen or a mixture thereof.
The use of daily dosage units consisting essentially a progestogen, and of an anti-progestogen, in the preparation of a drug delivery system, said drug delivery system characterized by consisting of daily dosage units containing only a progestogenic compound as therapeutically effective ingredient and two to seven dosage units comprising anti-progestogen, one of which is administered at the beginning, and the other or others divided regularly throughout the cycle.
The use of oral daily dosage units consisting essentially of an estrogen and a progestogen, and of an anti-progestogen, in the preparation of a drug delivery system, said drug delivery system characterized by consisting of daily dosage units containing progestogen and/or estrogen as therapeutically effective ingredient and two to seven dosage units comprising an anti-progestogen, one of which is administered at the beginning and the other or others divided regularly throughout the cycle.
Dependencies are inferred from the claim text.