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US 2001/0027181 A1Published application
Treatment or prophylaxis of ischemic heart disease
AssigneeDaiichi Suntory Pharma Co., Ltd.
InventorMasafumi Kitakaze
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AssigneeDaiichi Suntory Pharma Co., Ltd.
InventorMasafumi Kitakaze
Estimating the term…
The present invention provides a pharmaceutical composition and a method for reducing an infarct region resulting from the ischemic necrosis of cells, especially, a pharmaceutical composition and a method for suppressing ischemia-reperfusion injury in the treatment of ischemic heart disease. The pharmaceutical composition and the method utilize a substance, as an active ingredient, which can increase intracellular cGMP production by acting on a natriuretic peptide receptor, and which has the effect of reducing an infarct region. The substance is preferably a natriuretic peptide. The present invention is particularly useful for the treatment or prophylaxis of ischemic disease.
A pharmaceutical composition for use in treatment or prophylaxis of ischemic heart disease, the pharmaceutical composition containing a substance, as an active ingredient, which can increase intracellular cGMP production by acting on a natriuretic peptide receptor, and which has an effect of reducing an infarct region.
A method of treatment or prophylaxis of ischemic heart disease, comprising administering to a patient in need of such a treatment or prophylaxis a substance, as an active ingredient, which can increase intracellular cGMP production by acting on a natriuretic peptide receptor, and which has an effect of reducing an infarct region.
Dependencies are inferred from the claim text.