US 2001/0025027 A1Published application

Inhibition of ceramide for the prevention and treatment of oral mucositis induced by antineoplastic drugs or radiation

OwnerStephen T. Sonisinventor

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Abstract

Intervention for oral mucosal injury secondary to chemotherapy or radiation based on the inhibition in the synthesis of ceramide, blockage of its activity, or its digestion.

Claims3

Dependent claims

A method of treating, inhibiting, or preventing mucositis in a human patient, said method comprising administering to said patient an effective amount of a therapeutic composition comprising a compound that either inhibits the synthesis of ceramide, blocks the activity of ceramide, or degrades ceramide.

Dependencies are inferred from the claim text.

Facts

Application: 09/801,435Filed 7 Mar 2001
Priority: 7 Mar 2000
Published: 27 Sep 2001
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 31/357
Having oxygen as the only ring hetero atom, e.g. fungichromin: having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
A61K 31/198
The amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine,…:…
A61K 31/205
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids: amine addition salts of organic acids;…
A61K 31/336
Having oxygen as the only ring hetero atom, e.g. fungichromin: having three-membered rings, e.g. oxirane, fumagillin

Family

Application60/187,533Us provisional application · filed 7 Mar 2000
US 2001/0025027 A1This patent

From the US filing history. Foreign family members aren’t listed.

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