Compositions and methods for repair of osseous defects and accelerated wound healing
AssigneeUnicare Biomedical, Inc.
InventorShih-Liang S. Yang
Life of this patent
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Abstract
Compositions useful for repairing osseous defects and healing of wounds and burns include particulate bioactive and biocompatible glass including 40 to 58% by weight silica, 10 to 32% by weight calcia, 10 to 32% by weight soda, 2 to 10% by weight phosphorus pentoxide and 0 to 8% by weight silver oxide. The particles have a size distribution of: less than 500 microns. Methods for repairing osseous defects, healing wounds and burns utilizing such compositions are also provided.
Claims37
A composition useful to repair osseous defects, the composition comprising a particulate bioactive and biocompatible glass including an effective amount of an antimicrobial agent.
A composition useful to repair osseous defects, the composition consisting essentially of:
- particulate bioactive and biocompatible glass having the following chemical makeup:
- 32 Silica about 40% to about 58% by weight Calcia about 10% to about 32% by weight Soda about 10% to about 32% by weight Phosphorus pentoxide about 2% to about 10% by weight Antimicrobial agent about 0% to about 8% by weight
- and the following particle size distribution:
- about 20 microns to less than about 210 microns about 20% to about 65% by weight
- about 210 microns to less than about 297 microns about 20% to about 65% by weight
- about 297 microns to less than about 350 microns about 15. to about 55% by weight
- about 350 microns to less than about 420 microns about 0% to about 40% by weight
- the particle size distribution being measured using calibration sieves.
A composition useful for the healing of wounds and burns, the composition comprising a particulate bioactive and biocompatible glass including an effective amount of an antimicrobial agent.
Dependencies are inferred from the claim text.