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US 2001/0024637 A1Published application
Novel compositions for use in embolizing blood vessels
OwnerScott Evans, Richard J. Greff +1inventors
InventorsScott Evans, Richard J. Greff, James I. Wright
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Abstract
Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise a polymer, a biocompatible solvent and a contrast agent. The polymer is selected from the group consisting of polyacrylonitrile, polyurethane, polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid.
Claims27
A composition comprising:
- (a) from about 2.5 to about 8.0 weight percent of a polymer selected from the group consisting of polyacrylonitrile, polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid, and mixtures thereof;
- (b) from about 10 to about 40 weight percent of a contrast agent;
- (c) from about 52 to about 87.5 weight percent of a biocompatible solvent
- wherein the weight percent of the polymer, contrast agent and biocompatible solvent is based on the total weight of the complete composition.
1 more element
A method for embolizing a blood vessel by injecting into said blood vessel a sufficient amount of a composition comprising:
- (a) from about 2.5 to about 8.0 weight percent of a polymer selected from the group consisting of polyacrylonitrile, polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid, and mixtures thereof;
- (b) from about 10 to about 40 weight percent of a contrast agent;
- (c) from about 52 to about 87.5 weight percent of a biocompatible solvent
- wherein the weight percent of the polymer, contrast agent and biocompatible solvent is based on the total weight of the complete composition
- under conditions wherein a precipitate is formed which embolizes the blood vessel.
2 more elements
Dependencies are inferred from the claim text.