Novel interleukin compositions and methods of use
OwnerBeverly A. Blazar, Andrew C. Webbinventors
Life of this patent
Estimating the term…
Abstract
A novel immunoregulatory factor, designated IL-X, is described which has been isolated from an Epstein-Barr virus (EBV) infected lymphoblastoid cell line. IL-X is a growth factor for EBV transformed human B lymphocytes and for murine helper T lymphocytes. Also taught are methods of raising antibodies to IL-X, and cloning of IL-X.
Claims6
A purified IL-X polypeptide, comprising at least one amino acid sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, and SEQ ID NO:
- 6.
A purified IL-X polypeptide, having a molecular weight of approximately 42 kD as determined by SDS-PAGE or a fragment thereof sufficient to retain at least one biological activity selected from the group consisting of enhancing human B cell proliferation and enhancing human T cell proliferation, said polypeptide comprising at least one amino acid sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, and SEQ. ID NO:
- 6.
Dependencies are inferred from the claim text.