Single-dose antihistamine/decongestant formulations for treating rhinitis
AssigneeJ-Med Pharmaceuticals, Inc.
InventorsRobert E. Weinstein, Allan M. Weinstein
Life of this patent
Estimating the term…
Abstract
Pharmaceutical dosage forms for oral administration of an antihistamine and a decongestant are disclosed. The dosage forms provide an antihistamine in an amount and formulation to exhibit antihistaminic activity in a human for greater than 22 hours; and a decongestant in an amount and formulation to exhibit stimulatory activity in a human for less than 16 hours. The formulation of the invention can be taken once per day to afford symptomatic relief of rhinitis while avoiding stimulation at night.
Claims23
An oral dosage unit comprising:
- (a) an antihistamine in an amount and formulation to exhibit antihistaminic activity in a human for greater than 22 hours;
- and
- (b) a decongestant in an amount and formulation to exhibit stimulatory activity in a human for less than 16 hours.
A kit for treating rhinitis in a human comprising:
- (a) an oral dosage form containing an amount of an antihistamine to exhibit antihistaminic activity in a human for greater than 22 hours;
- (b) an oral dosage form containing an amount of a decongestant to exhibit stimulatory activity in a human for less than 16 hours;
- and
- (c) instructions to administer the antihistamine and decongestant at the start of the day.
A method of providing treatment for rhinitis in a human comprising:
- (a) formulating an amount of an antihistamine to exhibit antihistaminic activity in a human for greater than 22 hours;
- (b) formulating an amount of a decongestant to exhibit stimulatory activity in a human for less than 16 hours;
- (c) combining the antihistamine and the decongestant in a single oral dosage unit;
- and
- (d) providing instructions to administer the oral dosage unit at the start of the day.
Dependencies are inferred from the claim text.