US 2001/0011073 A1 · Uses of transgenic animals containing a type X collagen mutant

Abstract

This invention provides an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth. This invention provides a polypeptide encoded by the isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth. This invention also provides a polypeptide which comprise the portion of the mutated collagen X capable of regulating bone growth. This invention further provides a transgenic animal comprising an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth.

Claims20

Dependent claims

An isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth.

Dependencies are inferred from the claim text.

Facts

Application

09/794,919Filed 27 Feb 2001

Priority

8 Oct 1998

Published

2 Aug 2001

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

C12N 15/8509
For animal cells: for producing genetically modified animals, e.g. transgenic
A01K 67/0275
New or modified breeds of vertebrates: genetically modified vertebrates, e.g. transgenic
C07K 14/78
From animals; from humans: connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
A01K 2217/05
Genetically modified animals: animals comprising random inserted nucleic acids

Uses of transgenic animals containing a type X collagen mutant

Life of this patent

Uses of transgenic animals containing a type X collagen mutant

Life of this patent

Abstract

Claims20