Method and system for screening high developmental potential embryo for in-vitro fertilization

A method for screening high developmental potential embryo for in-vitro fertilization, comprising steps of:

• segmenting an embryo from an acquired multi-focus embryo image;
• segmenting a trophectodern (TE) image from the multi-focus embryo image after embryo segmentation, and unfolding the segmented TE image;
• inputting the multi-focus embryo image after the embryo segmentation, the TE image unfolded after the segmentation, biochemical features of a patient couple and status features of a maternal uterus into a trained prediction model, and outputting an embryo developmental potential score;
• and
• selecting an embryo with the highest score as the high developmental potential embryo,
• wherein the prediction model comprises a convolutional neural network (CNN) network, an attention module, a vision transformer (Vit) network, a multi-layer perceptron and a score fusion module;
• wherein the CNN network predicts an embryo developmental potential score from the multi-focus embryo image after the embryo segmentation, and the attention module is used to generate a weight of the embryo developmental potential score obtained from the multi-focus embryo image, and a weighted sum of all embryo developmental potential scores is taken as an embryo developmental potential score predicted from the multi-focus image;
• the Vit network is used to generate an embryo developmental potential score from the TE image unfolded after the segmentation;
• the multi-layer perceptron is used to generate an embryo developmental potential score from the biochemical features of the patient couple and the status features of the maternal uterus;
• and
• the score fusion module is used to fuse three embryo developmental potential scores predicted from the multi-focus embryo image after the embryo segmentation, the TE image unfolded after the segmentation, the biochemical features of the patient couple and the status features of the maternal uterus, respectively, and output a final embryo developmental potential score.