Longitudinal health outcome monitoring using an intelligent injection device platform

A research platform for tracking medication usage and patient biomarkers comprising:

• a server configured to receive administration data received from a wireless module of intelligent injection devices used within a healthcare entity;
• a database for storing treatment schedules, the administration data received from the wireless module of the intelligent injection devices, and biomarker measurements;
• a data collection system configured to collect biomarker data from connected monitoring devices;
• a compliance analysis module configured to calculate an adherence score by comparing actual administration timing and dosage to a prescribed treatment schedule, wherein the actual administration timing and dosage is received from the wireless module of the intelligent injection devices;
• a research analytics module configured to analyze a relationship between medication regimen adherence and a patient outcome, wherein the medication regimen adherence is determined based upon, at least in part, the administration data received from the wireless module of the intelligent injection devices;
• a reporting system configured to generate an observational study report correlating a drug adherence pattern with a biomarker change and a clinical outcome, wherein the drug adherence pattern is determined based upon, at least in part, the administration data received from the wireless module of the intelligent injection devices;
• and
• adjusting one or more chamber valves of at least one intelligent injection device of the intelligent injection devices to control delivery of the dosage.