Hemostatic, antibacterial, and healing-promoting clay mineral-based biomaterial and preparation method thereof

A method for preparing a hemostatic, antibacterial, and healing-promoting clay mineral-based hydrogel, comprising the following steps:

• dissolving chitosan uniformly in a dilute acid to obtain a chitosan solution, adding a preset amount of a crosslinking agent to obtain a first mixture, and stirring the first mixture to allow complete dissolution;
• and
• adding a kaolinite and Prussian blue (PB) composite to obtain a second mixture, thoroughly stirring the second mixture, and drying a resulting system at room temperature to obtain the hemostatic, antibacterial, and healing-promoting clay mineral-based hydrogel, wherein the kaolinite and PB composite comprises nano-kaolinite and PB in-situ growing on the nano-kaolinite;
• wherein a method for preparing the kaolinite and PB composite comprises the following steps:
• adding potassium ferricyanide and polyvinylpyrrolidone (PVP) to dilute hydrochloric acid, and subjecting a resulting mixture to stirring and an ultrasonic treatment at a room temperature to obtain a homogeneous solution;
• and
• adding the nano-kaolinite to the homogeneous solution to obtain a mixed solution, subjecting the mixed solution to an ultrasonic treatment and thorough stirring, and allowing a resulting system to stand to obtain the blue kaolinite and PB composite.