Nerve growth factor mutant
AssigneeStaidson (Beijing) Biopharmaceuticals Co., Ltd.
InventorsChao Wang, Lei Ma, Tianfei Du
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Abstract
Provided is a nerve growth factor mutant, wherein the nerve growth factor mutant is an amino acid sequence as shown by any one of SEQ ID No: 3 to SEQ ID No: 21 in the sequence listing. The advantage of the nerve growth factor mutant lies in that the mutation of a nerve growth factor can alleviate side effects such as pain, falling within the field of biological pharmacy.
Claims17
A nucleic acid comprising a nucleotide sequence encoding a nerve growth factor mutant, wherein the nerve growth factor mutant comprises Phe12Glu with reference to the amino acid positions set forth in a wild-type human nerve growth factor.
A nucleic acid encoding a nerve growth factor mutant, wherein the nerve growth factor mutant comprises Phe12Glu with reference to the amino acid positions set forth in a wild-type human nerve growth factor.
Dependencies are inferred from the claim text.