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US 12,766,159 B2Granted
Glycyrrhizin-branched polyethylene glycol conjugate for treating cancer
AssigneeIucf-Hyu (Industry-University Cooperation Foundation Hanyang University)
InventorsDong Yun Lee, Min Su Kim
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Abstract
The present invention relates to a glycyrrhizin-branched polyethylene glycol conjugate and a use thereof for treating cancer, wherein the glycyrrhizin-branched PEG conjugate exhibits anti-cancer effects better than those of glycyrrhizin and increases blood half-life, and thus can be effectively used for treating cancer.
Claims7
A method of treating cancer comprising administering a pharmaceutical composition for treating cancer comprising the conjugate as an active ingredient as follows:
- (a) glycyrrhizin;
- and
- (b) branched polyethylene glycol linked to the glycyrrhizin by a covalent bond,
- wherein the branched polyethylene glycol is 4-arm polyethylene glycol, and its molecular weight is 1 to 4 kDa.
1 more element
Dependencies are inferred from the claim text.