Method of use for benzofuran compounds

A method of preparing an immunotherapy, comprising:

• obtaining an antigen-presenting cell from a patient in need thereof;
• exposing the antigen-presenting cell with a therapeutically effective amount of a first compound and a therapeutically effective amount of a second compound;
• wherein the first compound is (2E)-3-(1-benzofuran-5-yl) prop-2-enoic acid;
• wherein the second compound is an antigen molecule;
• incubating the antigen-presenting cell with the first compound and the second compound for at least one hour to form a primed antigen-presenting cell;
• and
• injecting the primed antigen-presenting cell into the patient.

A method of preparing an in vivo immunotherapy, comprising:

• testing dendritic cell populations and CD8+ t-cells of a patient in need of tumor treatment;
• confirming the dendritic cell populations and CD8+ t-cells of the patient in need of tumor treatment meets or exceeds a minimum threshold value;
• administering a therapeutically effective amount of an antitumor therapy to the patient in need of tumor treatment;
• wherein the antitumor therapy is chemotherapy, radiation, immunotherapy, hyperthermia, or photodynamic therapy;
• and
• administering a therapeutically effective amount of a first compound to the patient in need of tumor treatment orally, intravenously, intra-arterially, intrathecally, or intraventricularly;
• wherein the first compound is (2E)-3-(1-benzofuran-5-yl) prop-2-enoic acid.