Assay apparatuses, methods and reagents
AssigneeMeso Scale Technologies, LLC.
InventorsIan D. Chamberlin, Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Manish Kochar, Sandor Kovacs, D.T. Le, Aaron Leimkuehler, George Sigal, Leo Tabakin, Jon Willoughby
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Abstract
Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
Claims20
A method for interrogating samples contained in a multi-well plate having a M×N matrix of wells, comprising the steps of:
- (a) providing a contact platform having a plurality of interrogation zones,
- (b) providing at least a pair of electrical contacts for each interrogation zone, wherein each interrogation zone is adapted to interrogate a single well,
- (c) applying, selectively, a voltage potential to:
- (i) one interrogation zone to interrogate one or more wells simultaneously or (ii) the plurality of interrogation zones to interrogate a plurality of wells, and
- (d) moving the multi-well plate relative to the contact platform to interrogate additional wells.
An instrument configured to interrogate samples contained in a multi-well plate having a M×N matrix of wells, comprising:
- a contact platform having a plurality of interrogation zones;
- at least a pair of electrical contacts for each of the plurality of interrogation zones, wherein each of the plurality of interrogation zones is adapted to interrogate a single well;
- and
- a voltage source configured for selectively applying a voltage potential to:
- (i) one interrogation zone to interrogate one or more wells simultaneously, or (ii) the plurality of interrogation zones to interrogate a plurality of wells.
An instrument configured to interrogate samples contained in a multi-well plate, comprising:
- a contact platform having a plurality of interrogation zones;
- at least a pair of electrical contacts for each of the plurality of interrogation zones, wherein each of the plurality of interrogation zones is adapted to interrogate a single well;
- and
- a voltage source configured for selectively applying a voltage potential to:
- at least one interrogation zone to interrogate one or more wells.
Dependencies are inferred from the claim text.