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US 12,760,071 B2Granted
Supramolecular polypeptide compositions and methods of making and using the same
AssigneeDuke University
InventorsJoel Collier, Nicole Votaw
Life of this patent
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Abstract
The present disclosure provides a supramolecular (self-assembling) polypeptide complex that comprises a plurality of randomized polyamino acids that self-assemble into nanofibers and methods of making and using same.
Claims13
A polypeptide molecule consisting of a self-assembling polypeptide consisting of SEQ ID NO:1 (Q11) linked to a random polypeptide at least ten amino acids in length, wherein each amino acid in the random polypeptide is independently selected from lysine, glutamic acid, tyrosine, and alanine;
- and optionally wherein the self-assembling polypeptide is linked to the random polypeptide via a spacer, wherein the spacer is a polypeptide and is at least three amino acids in length and less than 10 amino acids in length.
Dependencies are inferred from the claim text.