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US 12,760,045 B2Granted
3-pyrrolidine-indole derivatives as serotonergic psychedelic agents for the treatment of CNS disorders
AssigneeMindset Pharma Inc.
InventorsAbdelmalik Slassi, Joseph Araujo
Life of this patent
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Abstract
The present application relates to 3-cyclic amine-indole derivatives of general Formula (I), to processes for their preparation, to compositions comprising them and to their use in activation of a serotonin receptor in a cell, as well as to treating diseases, disorders or conditions by activation of a serotonin receptor in a cell. The diseases, disorders or conditions include, for example, psychosis, mental illnesses, and other neurological diseases, disorders and conditions.
Claims18
A method for treating a mental illness selected from:
- depression, depression in Alzheimer's disease, treatment resistant depression, depression in terminally ill cancer patients, major depressive disorder, post-traumatic stress disorder (PTSD), mood disorders and major depressive disorder, comprising administering a therapeutically effective amount of one or more compounds or a pharmaceutically acceptable salt thereof, selected from:
- Com-
- pound
- ID #
- Chemical Structure
- I-1
- I-2
- I-3
- I-4
- I-5
- I-6
- I-7
- I-8
- I-9
- I-10
- I-11
- I-12
- I-13
- I-14
- I-15
- I-16
- I-17
- I-18
- I-19
- I-20
- I-21
- I-22
- I-23
- I-24
- I-25
- I-26
- 1-27
- I-28
- 1-29
- 1-30
- 1-31
- 1-32
- 1-33
- 1-34
- 1-35
- 1-36
- I-37
- I-38
- I-39
- I-40
- I-41
- I-42
- I-43
- I-44
- I-45
- I-46
- I-48
- I-49
- I-50
- I-51
- I-52
- I-53
- I-54
- to a patient in need thereof.
56 more elements
Dependencies are inferred from the claim text.