Wearable ultrasound device and harness for immunomodulation, and uses thereof

A system for securing an ultrasound transducer over a spleen of a subject, the system comprising:

• a harness comprising:
• a front portion configured to hold a power pack and configured to be positioned over the subject's chest;
• a rear portion configured to be positioned over the subject's back, and connected to the front portion by a first shoulder strap and a second shoulder strap,
• wherein each shoulder strap comprises shoulder strap scales that extend lengthwise along each shoulder strap for adjustment to a set length every time the harness is worn by the subject,
• wherein a connection region between the first shoulder strap and the rear portion and a connection region between the second shoulder strap and the rear portion comprise an adjustable clasp,
• wherein the adjustable clasp is configured to connect and disconnect and adjust a connection position between the rear portion and the first shoulder strap or the rear portion and the second shoulder strap,
• wherein the connection position comprises an overlap region between the first shoulder strap and the rear portion and the second shoulder strap and the rear portion;
• an adjustable waist strap configured to wrap around a subject's waist and connect the front portion and the rear portion, wherein the adjustable waist strap comprises a waist strap scale that extends lengthwise along the adjustable waist strap for adjustment to a set length every time the harness is worn by the subject;
• and
• a transducer securing portion located on the adjustable waist strap and configured to be positioned over a spleen of a subject,
• wherein the transducer securing portion comprises a two-dimensional transducer securing portion scale that extends length-wise and height-wise along the exterior of the transducer securing portion,
• wherein the two-dimensional transducer securing portion scale is benchmarked relative to an anatomical landmark of the subject and is configured to align the ultrasound transducer so that the ultrasound transducer is placed in the same position inside the transducer securing portion every time the harness is worn by the subject;
• and
• a treatment unit comprising:
• the ultrasound transducer configured to couple to the transducer securing portion of the harness, wherein the ultrasound transducer is positioned in the same location above the subject's spleen every time the harness is worn.