Pharmaceutical composition for improving respiratory damage and use for manufacturing pharmaceutical composition for improving respiratory damage
OwnerMing-Chien Hunginventor
Life of this patent
Estimating the term…
Abstract
The present invention provides a pharmaceutical composition for improving respiratory damage. The pharmaceutical composition includes an adsorbent medicament and a water-containing carrier, wherein said adsorbent medicament comprises a carbon material, a molecular sieve or a positively and negatively charged compound. The present invention also provides use for manufacturing pharmaceutical composition for improving respiratory damage.
Claims7
A pharmaceutical composition for improving respiratory damage, comprising an adsorbent medicament, wherein said adsorbent medicament comprises a carbon material and a water-containing carrier,
- wherein said carbon material is selected from a group consisting of activated carbon, activated carbon fiber, activated carbon ball, columnar activated carbon, activated carbon powder, and a combination thereof,
- wherein said carbon material has a mean particle diameter ranging from 0.1 to 500 μm,
- wherein said carbon material has a specific surface area (BET) ranging from 300 to 3000 m2/g,
- wherein said carbon material has a micropore diameter ranging from 1 to 500 nm, wherein said water-containing carrier is selected from the group consisting of normal saline, buffers, isotonic saline solution, and a combination thereof, said adsorbent medicament mixed with said water-containing carrier is formulated as a suspension at a concentration ranging from 0.001 to 1 wt %,
- wherein the adsorbent carbon material is configured for administration into a respiratory system by inhalation or instillation to be delivered to a respiratory tract, lungs, or alveoli, to adsorb toxic substances, bacteria, viruses, proinflammatory cytokines, chemokines, or cytokines in the respiratory system, and
- wherein the pharmaceutical composition improves respiratory system damage.
A method for improving respiratory damage, the method comprising:
- (a) providing a pharmaceutical composition comprising an adsorbent medicament, wherein said adsorbent medicament comprises a carbon material and a water-containing carrier;
- (b) administering said pharmaceutical composition into a respiratory system of the patient by inhalation or instillation to deliver the carbon material to a respiratory tract, lungs, or alveoli, to adsorb toxic substances, bacteria, viruses, proinflammatory cytokines, chemokines, or cytokines in the respiratory system;
- and
- (c) removing the pharmaceutical composition out of the lungs of the patient,
- wherein said carbon material is selected from the group consisting of activated carbon, activated carbon fiber, activated carbon ball, columnar activated carbon, activated carbon powder, and a combination thereof,
- wherein said carbon material has a mean particle diameter ranging from 0.1 to 500 μm, a specific surface area (BET) ranging from 300 to 3000 m2/g, and a micropore diameter ranging from 1 to 500 nm,
- wherein said water-containing carrier is selected from the group consisting of normal saline, buffers, isotonic saline solution, and a combination thereof, and wherein said adsorbent medicament mixed with said water-containing carrier is formulated as a suspension at a concentration ranging from 0.001 to 1 wt %.
Dependencies are inferred from the claim text.