Ultrasound diagnostic tool for renal fibrosis assessment

An ultrasound diagnostic tool for renal fibrosis assessment, comprising a processor coupled to a memory, a fixed storage system, a renal ultrasound system, and an output bus, wherein the fixed storage system and/or the memory is configured to store a computer code, and the processor is configured to execute the computer code for:

• performing a series of renal ultrasound measurements on a patient diagnosed with chronic kidney disease and having an age to obtain a set of renal ultrasound data;
• evaluating the renal ultrasound data to obtain:
• at least one morphological parameter comprising a renal length of the kidney;
• and
• at least one hemodynamic parameter comprising an end-diastolic velocity of an interlobar renal artery;
• performing a multivariate diagnostic calculation combining the age, the at least one morphological parameter and the at least one hemodynamic parameter to obtain a risk assessment which evaluates the patient's risk of developing moderate-to-severe renal fibrosis;
• outputting the risk assessment through the output bus to a display and/or a printer and/or a remote device for use by a health-care professional in determining a monitoring and/or treatment plan for the patient.

An ultrasound diagnostic tool for renal fibrosis assessment comprising:

• a) a renal ultrasound system which produces renal ultrasound data related to a kidney of a patient having an age, wherein the patient is a person diagnosed with chronic kidney disease;
• b) an ultrasound measurement system which evaluates the renal ultrasound data to measure at least one morphological parameter comprising a renal length of the kidney and at least one hemodynamic parameter comprising an end-diastolic velocity of the interlobar renal artery;
• and
• c) a diagnostic system which performs at least one diagnostic calculation on the age, the at least one morphological parameter, and the at least one hemodynamic parameter to obtain a risk assessment which predicts the patient's risk of developing moderate-to-severe renal fibrosis, wherein the risk assessment uses an increased risk of 6 percent per additional year of the age, an increased risk of 58 percent for every one unit decrease in the renal length, and an increased risk of 20 percent for every one unit decrease in the end-diastolic velocity, in predicting the patient's risk of developing moderate-to-severe renal fibrosis.

An ultrasound diagnostic tool for renal fibrosis assessment, comprising a processor coupled to a memory, a fixed storage system, a renal ultrasound system, and an output bus, wherein the fixed storage system and/or the memory is configured to store a computer code, and the processor is configured to execute the computer code for:

• a) performing a series of renal ultrasound measurements on a patient diagnosed with chronic kidney disease and having an age to obtain a set of renal ultrasound data;
• b) evaluating the renal ultrasound data to obtain at least one morphological parameter comprising a renal length of the kidney and at least one hemodynamic parameter comprising an end-diastolic velocity of the interlobar renal artery;
• c) performing at least one diagnostic calculation on the at least one morphological parameter and the at least one hemodynamic parameter to obtain a risk assessment which evaluates the patient's risk of developing moderate-to-severe renal fibrosis, wherein the risk assessment uses an increased risk of 6 percent per additional year of the age of the patient, an increased risk of 58 percent for every one unit decrease in the renal length, and an increased risk of 20 percent for every one unit decrease in the end-diastolic velocity;
• and
• d) outputting the risk assessment through the output bus to a display and/or a printer and/or a remote device which can display the risk assessment to a health-care professional.