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US 12,746,220 B2Granted
Pharmaceutical composition for treatment or prevention of ischemic cardiovascular disease
AssigneeIndustry-Academic Cooperation Foundation, Yonsei University
InventorsYoung Sup Yoon, Ki Bum Lee, Hyeon Yeol Cho, Sy-Tsong Chueng
Life of this patent
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Abstract
Provided in the present specification is an ETV2 transcription factor comprising: a polyamide comprising a domain binding to DNA (DNA binding domain) of an ETV2 gene; a nuclear localization signal peptide; and a nano-particle.
Claims10
An ETV2 transcription factor comprising:
- a polyamide having a DNA binding domain for an ETV2 gene;
- a nuclear localization signal peptide comprising SEQ ID NO:
- 2;
- and
- a nano-particle onto which the polyamide and the nuclear localization signal peptide are attached,
- wherein the polyamide has the following structure:
- and
- wherein the polyamide binds to a binding site of the ETV2 gene.
5 more elements
Dependencies are inferred from the claim text.