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US 12,697,419 B2Granted
Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
AssigneeBoard of Regents, The University of Texas System
InventorsSarah Mayes, Christine E. Schmidt
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Abstract
A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
Claims17
An apparatus comprising:
- a wrap comprising first and second layers;
- wherein the first layer includes a desiccated, translucent, amorphous hydrogel film, the hydrogel film comprising hyaluronic acid and sodium alginate;
- wherein the second layer includes collagen;
- wherein the first layer is fused to the second layer;
- wherein the first layer has at least 1% hyaluronic acid by dry weight.
2 more elements
Dependencies are inferred from the claim text.