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US 12,673,205 B2Granted
Treatment of inflammation by selective DMV cholinergic neuron stimulation
AssigneeThe Feinstein Institutes for Medical Research
InventorsAdam M. Kressel, Valentin A. Pavlov, Sangeeta S. Chavan, Kevin J. Tracey
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Abstract
Methods for electrical modulation of inflammation or serum TNF levels in a subject.
Claims6
A method of artificially increasing splenic norepinephrine release in a subject comprising selectively artificially electrically stimulating cholinergic neurons in a dorsal motor nucleus of a vagal nerve of the subject, wherein no other source of vagal nerve activity is artificially electrically stimulated, effective to increase splenic norepinephrine release.
Dependencies are inferred from the claim text.