Functionalized enzyme-powered nanomotors
AssigneesFundació Institut De Bioenginyeria De Catalunya, Institució Catalana De Recerca I Estudis AvançAts
InventorsSamuel Sañchez Ordoñez, Tania Patiño Padial, Ana Candida Lopes Hortelão
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Abstract
The present invention provides an enzyme-powered nanomotor, comprising a particle with a surface, an enzyme, and a heterologous molecule; characterized in that the enzyme and the heterologous molecule are discontinuously attached over the whole surface of the particle. The invention also provides the nanomotor for use in therapy, diagnosis and prognosis, in particular, for the treatment of cancer. Additionally, the invention provides the use of the nanomotor for detecting an analyte in an isolated sample.
Claims15
An enzyme-powered non-Janus nanomotor capable of self-propelling, comprising:
- a particle with a surface;
- a propelling enzyme;
- and
- a heterologous molecule;
- wherein the propelling enzyme and the heterologous molecule are discontinuously attached over the whole surface of the particle, and wherein the particle is spherical.
Dependencies are inferred from the claim text.