High pressure inhalation device

An inhalation device for generation of an aerosol of a medically active liquid, the inhalation device comprising:

• a housing comprising therein:
• a reservoir configured to store the medically active liquid;
• a pumping unit located downstream from the reservoir;
• a nozzle located downstream from the pumping unit;
• the pumping unit comprising a hollow cylindrical part and a piston, the hollow cylindrical part having an interior space with a defined cross section configured to receive an end portion of the piston, wherein the hollow cylindrical part and the piston are linearly moveable relative to one another forming a pumping chamber with a variable volume;
• a plunger mechanically coupled to the piston or to the hollow cylindrical part of the pumping unit and having a cross section larger than the cross section of the hollow cylindrical part, the plunger configured to translate in a reciprocating linear movement within the housing;
• and
• a pressure chamber having a variable internal volume defined by the housing and a position of the plunger in the housing, the pressure chamber configured to receive a pressurized gas, wherein
• the pressure chamber comprises an inlet valve and an outlet valve with separate ports into the pressure chamber, and
• the pressurized gas is configured to exert a force on and translate the plunger within the housing increasing the variable internal volume of the pressure chamber and delivering mechanical energy to the pumping unit to decrease the variable volume of the pumping chamber and generate the aerosol of the medically active liquid.