Method and system of multi-parametric magnetic resonance imaging

A magnetic resonance imaging (MRI) system, comprising:

• an MR scanning device, configured to acquire multiple parallel, segmented acquisitions from an object positioned in an examination volume of the MR scanning device;
• wherein the MR scanning device is configured to:
• apply an R2 sensitizing phase;
• acquire a first acquisition;
• apply an R1 sensitizing phase;
• acquire a second acquisition;
• wait for a delay time;
• and
• acquire a third acquisition;
• wherein each acquisition comprises measuring at least three echoes at different echo times (TE);
• and
• a processing circuit, configured to calculate multiple physical properties of the object based on at least some of the at least three acquisitions, wherein to calculate multiple physical properties of the object comprises:
• to calculate a water fraction and a fat fraction based on at least two echoes of the at least three echoes of at least one acquisition of the multiple parallel, segmented acquisitions;
• and
• to calculate a macro-molecular fraction by using 100% subtracting a sum of the water fraction and the fat fraction.