All-in-one ultrasound systems and methods including histotripsy

An ultrasound system driving architecture configured to drive an ultrasound transducer array with a plurality of ultrasound modalities, the ultrasound system driving architecture comprising:

• a power supply switching circuit configured to switch between a first power mode that provides a first voltage and a first current and a second power mode that provides a second voltage and a second current, wherein the second voltage is higher than the first voltage and the second current is lower than the first current;
• and
• a current driver circuit comprising a gate driver configured to receive a digital drive signal, a transformer electrically coupled to the ultrasound transducer array, a transistor electrically coupled to the gate driver and the transformer, and a first resistor and a first capacitor electrically coupled to the transistor and configured to slow down a turn-on time and a turn-off time of the transistor to reduce RF noise emissions, wherein the gate driver is configured to drive the transistor at a first pulse repetition frequency when the power supply switching circuit is operating in the first power mode to produce ultrasound pulses of a first ultrasound therapy modality, and wherein the gate driver is configured to drive the transistor at a second pulse repetition frequency when the power supply switching circuit is operating in the second power mode to produce ultrasound pulses of a second ultrasound therapy modality.