Systems and methods for perivascular nerve denervation

A catheter apparatus for perivascular nerve denervation, comprising:

• a shaft having a distal end;
• and
• a loop disposed near the distal end and configured to curl around a tissue and receive, via the shaft, energy to denervate at least a portion of the tissue,
• wherein the loop is configured to curl as the loop emerges distally from the distal end of the shaft and includes:
• a first film capable of bending to curl around the tissue and a plurality of electrodes disposed on the first film and the plurality of electrodes are made of a two-way shape-memory alloy,
• wherein the plurality of electrodes include a first electrode extended along a direction in which the loop is configured to emerge from the shaft to deliver thermal energy to a first treatment zone of the tissue and a second electrode extended along the direction in which the loop is configured to emerge from the shaft to deliver thermal energy to a second treatment zone of the tissue, and
• wherein when the energy is received by the first electrode and the second electrode, the first electrode and the second electrode localize heat distribution between the first electrode and the second electrode so that the thermal energy delivered by the first electrode and the second electrode is localized between the first treatment zone and the second treatment zone.