Spatiotemporal-based detection and correction of motion artifact for measurement of arterial pressure waveform

A system for management of a motion artifact, comprising:

• a sensor array configured to be in contact with a surface patch of a skin of a subject, the system having a camera that captures image data of the sensor array;
• and
• a controller, communicatively coupled to the camera, configured to:
• measure an arterial pressure waveform based on the image data, wherein the arterial pressure waveform comprises a motion artifact caused by movement of a body part of the subject or an external movement imparted to the subject, which has an effect on a respective deformation or movement of the sensor array on the skin over (a) the artery in a pulsatile area in response to positive pressure being applied thereto and over (b) the skin adjacent to the artery in a non-pulsatile area,
• determine information relating to the motion artifact affecting the pulsatile area and the non-pulsatile area,
• correct the arterial pressure waveform by removing the motion artifact based on the determined information to produce a corrected arterial pressure waveform, and
• determine the physiological parameters of the subject based on the corrected arterial pressure waveform in which the motion artifact is suppressed based on at least the information relating to the motion artifact in the non-pulsatile area,
• wherein the information of the motion artifact in the pulsatile area and the non-pulsatile area is determined by:
• detecting the motion artifact in the pulsatile area;
• detecting the motion artifact in the non-pulsatile area;
• and
• determining spatiotemporal information of the motion artifact in the pulsatile area and in the non-pulsatile area,
• wherein the system captures image data of both the pulsatile area and the non-pulsatile area from the sensor array, the controller being further configured to digitally separate the pulsatile area and the non-pulsatile area in the image data by:
• estimating a displacement of the image data at each time point;
• determining a variance of a signal over time based on the displacement;
• performing a temporal Fourier transform of the displacement of the image data at all locations based on the variance of the signal over time;
• determining areas with the transformed displacement that meet a predefined threshold;
• and
• segmenting the determined areas with the transformed displacement that meet the predefined threshold into the pulsatile area and the areas with the transformed displacement that does not meet the predefined threshold into the non-pulsatile area.

A method for correction of motion artifacts affecting a physiological waveform, the method comprising the steps of:

• receiving image data from a sensor array configured to be in contact with a skin of a subject;
• analyzing the image data to characterize a physiological waveform that includes motion artifact caused by movement of a body part of the subject or an external movement imparted to the subject, which has an effect (a) on sensor array deformation or movement on the skin over an artery in a pulsatile area in response to an external positive pressure being applied thereto and (b) on sensor array deformation or movement over the skin adjacent to the artery in a non-pulsatile area;
• determining information relating to the motion artifact affecting the pulsatile area and the non-pulsatile area;
• correcting the physiological waveform by removing or suppressing the motion artifact based on at least the information relating to the motion artifact in the non-pulsatile area to produce a corrected physiological waveform;
• and
• determining physiological parameters of the subject based on the corrected physiological waveform that does not include the motion artifact based on at least the information relating to the motion artifact in the non-pulsatile area,
• wherein the physiological waveform is representative of an arterial pressure, and wherein the determining the information comprises:
• detecting a characteristic of the motion artifact in the pulsatile area;
• detecting the characteristic or another characteristic of the motion artifact in the non-pulsatile area;
• determining the information of the motion artifact in the pulsatile area and the motion artifact in the non-pulsatile area,
• wherein the sensor array is trained on both the pulsatile area and the non-pulsatile area, the method further comprising digitally separating by a controller the pulsatile area and the non-pulsatile area in the image data by:
• estimating a displacement of the image data at each time point;
• determining a variance of a signal over time based on the displacement;
• performing a temporal Fourier transform of the displacement of the image data at all locations based on the variance of the signal over time;
• determining areas with the transformed displacement that meet a predefined threshold;
• and
• segmenting the areas with the transformed displacement that meet the predefined threshold into the pulsatile area and the areas with the transformed displacement that does not meet the predefined threshold into the non-pulsatile area.

A method for correction of motion artifacts affecting a physiological waveform, the method comprising the steps of:

• receiving image data from a sensor array configured to be in contact with a skin of a subject;
• analyzing the image data to characterize a physiological waveform that includes motion artifact caused by movement of a body part of the subject or an external movement imparted to the subject, which has an effect (a) on sensor array deformation or movement on the skin over an artery in a pulsatile area in response to an external positive pressure being applied thereto and (b) on sensor array deformation or movement over the skin adjacent to the artery in a non-pulsatile area;
• determining information relating to the motion artifact affecting the pulsatile area and the non-pulsatile area;
• correcting the physiological waveform by removing or suppressing the motion artifact based on at least the information relating to the motion artifact in the non-pulsatile area to produce a corrected physiological waveform;
• and
• determining physiological parameters of the subject based on the corrected physiological waveform that does not include the motion artifact based on at least the information relating to the motion artifact in the non-pulsatile area,
• wherein the physiological waveform is representative of an arterial pressure, and wherein the determining the information comprises:
• detecting a characteristic of the motion artifact in the pulsatile area;
• detecting the characteristic or another characteristic of the motion artifact in the non-pulsatile area;
• determining the information of the motion artifact in the pulsatile area and the motion artifact in the non-pulsatile area,
• wherein the detecting the characteristic of the motion artifact in the non-pulsatile area comprises:
• determining a plurality of parameters associated with the non-pulsatile area;
• determining at least one reference region in the image data based on the plurality of parameters associated with the non-pulsatile area;
• filtering out a residual pulsatile signal from at least one reference region to produce a pulse-free reference signal;
• and
• detecting the characteristic of the motion artifact in the non-pulsatile area based on the pulse-free reference signal from at least one reference region.

A system for management of a motion artifact, comprising:

• a sensor array configured to be in contact with a surface patch of a skin of a subject, the system having a camera that captures image data of the sensor array;
• and
• a controller, communicatively coupled to the camera, configured to:
• measure an arterial pressure waveform based on the image data, wherein the arterial pressure waveform comprises a motion artifact caused by movement of a body part of the subject or an external movement imparted to the subject, which has an effect on a respective deformation or movement of the sensor array on the skin over (a) the artery in a pulsatile area in response to positive pressure being applied thereto and over (b) the skin adjacent to the artery in a non-pulsatile area,
• determine information relating to the motion artifact affecting the pulsatile area and the non-pulsatile area,
• correct the arterial pressure waveform by removing the motion artifact based on the determined information to produce a corrected arterial pressure waveform, and
• determine the physiological parameters of the subject based on the corrected arterial pressure waveform in which the motion artifact is suppressed based on at least the information relating to the motion artifact in the non-pulsatile area,
• wherein the correcting the arterial pressure waveform comprises:
• detecting a type of motion artifact present in the pulsatile area and the non-pulsatile area;
• detecting whether an artifact flag is raised;
• and
• applying a correction technique to remove the motion artifact from the arterial pressure waveform based on at least the information, the raised artifact flag, and the type of motion artifact in the pulsatile area and the non-pulsatile area.