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US 12,595,293 B2Granted
Anti-follicle stimulating hormone receptor antibodies
AssigneeThe Wistar Institute
InventorsAlfredo Perales-Puchalt, David B. Weiner
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Abstract
The present invention relates to an isolated antibody or antigen binding fragment thereof that bind specifically to the Follicle Stimulating Hormone Receptor (FSHR). Also provided are methods for treating a disease in a subject comprising administering to the subject an isolated antibody or antibody fragment thereof that binds FSHR.
Claims14
An isolated antibody or antigen binding fragment thereof that binds Follicle Stimulating Hormone Receptor (FSHR), wherein the isolated antibody or antigen binding fragment thereof comprises:
- A) a heavy chain comprising:
- (i) a heavy chain CDR1 having the sequence of SEQ ID NO:
- 6;
- (ii) a heavy chain CDR2 having the sequence of SEQ ID NO:
- 7;
- and
- (iii) a heavy chain CDR3 having the sequence of SEQ ID NO:
- 8;
- and
- B) a light chain comprising:
- (i) a light chain CDR1 having the sequence of SEQ ID NO:
- 2;
- (ii) a light chain CDR2 having the sequence of SEQ ID NO:
- 3;
- and
- (iii) a light chain CDR3 having the sequence of SEQ ID NO:
- 4.
14 more elements
Dependencies are inferred from the claim text.