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US 12,595,232 B2Granted
DRG-MDM2-1 for use as a novel Mouse Double Minute 2 (MDM2) inhibitor
AssigneesBahcesehir Universitesi, Istanbul Teknik Universitesi
InventorsTimucin Avsar, Serdar Durdagi, Muge Didem Orhan, Maide Nur Paksoy, Gulsah Aydin, Mine Yurtsever
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Abstract
The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
Claims2
A pharmaceutical composition comprising an effective amount of a compound of Formula I, or a pharmaceutically acceptable derivative thereof,
- and one or more additional pharmaceutically active agents selected from the group consisting of anti-proliferative agents, immunomodulatory agents, antiviral agents, antimicrobial agents, anti-infective agents, anesthetic agents, antiemetics, and combinations thereof,
- wherein the pharmaceutically acceptable derivative of Formula I is a hydrate, a solvate, a stereoisomer, a salt, or a tautomer thereof.
Dependencies are inferred from the claim text.