Immunodulating small molecules
AssigneeAyuvis Research, Inc.
InventorsSuchismita Acharya, Santosh K. Panda
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AssigneeAyuvis Research, Inc.
InventorsSuchismita Acharya, Santosh K. Panda
Estimating the term…
The present invention includes novel compositions and methods for treating comprising a compound with the Formula I: wherein n=0, 1, 2, 3, 4, or 5; X=NH or O or S; Y=phenyl, or a phenyl group substituted with at least one methyl, a phenyl group substituted with at least one nitro, a phenyl group substituted with at least one nitrogen, a phenyl group substituted with at least one boron, aryl, substituted aryl, heteroaryl, four to six membered cycloalkyl, four to six membered heterocycloalkyl; R=H, C(O)R2, SO2R2; R1=H, C(O)R2, SO2R2; R2=Ethyl, methyl, isopropyl, n-propyl, t-butyl, n-butyl, NH2, NR3R4; R3, R4=Ethyl, methyl, isopropyl, n-propyl, t-butyl, n-butyl, three to six membered cycloalkyl, and Z=NH, or O, or none, and optionally wherein both X and Z are not both S, and wherein the amount of the compound is selected to either inhibit or activate the immune response.
A composition for modulating an immune response, wherein the composition comprises at least one molecule selected from
A method of treating a subject in need of immunomodulation comprising:
A compound selected from:
Dependencies are inferred from the claim text.