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US 12,594,028 B1Granted
EEG montage for facilitating selection of drug treatment in patients suffering from psychiatric disorders
AssigneeAlto Neuroscience, Inc.
InventorsAmit Etkin, Sarah Long, Iliana Bray, Akshay Sujatha Ravindran
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Abstract
This invention relates to the use of a reduced number of electroencephalogram (EEG) channels for predicting those who would benefit from drug treatment (such as with agomelatine) in patients with a psychiatric disorder (such as depression), as well as to an electroencephalogram (EEG) device for recording EEG data at these EEG channels.
Claims8
A method of selecting a patient suffering from depression for an agomelatine treatment and treating the patient, the method comprising:
- collecting brain wave activity data via a configuration of EEG electrodes applied to the patient, wherein the configuration is a 7-channel electrode configuration consisting of EEG electrodes at:
- F7-Fz-F8-Cz-P7-Pz-P8, according to the 10-10 system of electrode placement;
- analyzing the brain wave activity data to calculate one or more EEG measures, wherein at least one of the one or more EEG measures are selected from a group consisting of:
- an EEG measure of entropy, an EEG measure of complexity, or any combination thereof;
- predicting an outcome of the agomelatine treatment in the patient based on the one or more EEG measures;
- selecting the patient for agomelatine treatment based on the outcome prediction;
- and
- when the patient is selected for agomelatine treatment based on the one or more EEG measures, administering an effective amount of agomelatine, a prodrug thereof, or a pharmaceutically acceptable salt thereof to treat the depression of the patient.
5 more elements
Dependencies are inferred from the claim text.