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US 12,594,024 B2Granted
Method for predicting survival of non small cell lung cancer patients with brain metastasis
AssigneeThe Catholic University of Korea Industry-Academic Cooperation Foundation
InventorsSeung Ho Yang, Young Il Kim, Hyun Ho Kim
Life of this patent
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Abstract
The present invention relates to a method for predicting survival of non-small cell lung cancer patients with brain metastasis. More specifically, it proposes a method that is useful for predicting the survival of the patients by comparing TMTrg of the patients with cut off value for predicting long term survival.
Claims3
A method of treating a patient diagnosed with a non-small cell lung cancer with brain metastasis, the method comprising:
- (a) calculating a temporal muscle thickness reduction gradient (TMTrg) from the patient as calculated by:
- TMTrg=(Final temporal muscle thickness (TMT)−Initial TMT)/Follow-up period,
- wherein,
- the Final TMT is a TMT measured at a survival prediction point and is measured in millimeters (mm);
- the Initial TMT is a TMT measured at initial diagnosis of the patients' brain metastasis and measured in mm;
- and
- the Follow-up period is an interval between Initial TMT measurement time point and Final TMT measurement time point and measured in months;
- and
- (b) treating the patient with surgery, chemotherapy, radiation, or administering a therapeutic agent when the calculated TMTrg is −0.185 or more and less than 0.
6 more elements
Dependencies are inferred from the claim text.