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US 12,593,986 B2Granted
Transmission mode-photoacoustic tomography of the human brain through an acoustic window
AssigneeCalifornia Institute of Technology
InventorsYang Zhang, Sri Sai Narasimha KS Dhara Venkata, Lihong Wang
Life of this patent
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Abstract
Photoacoustic imaging techniques that deliver diffuse light in transmission mode to the brain and detect acoustic waves transmitted through an acoustic window in the skull.
Claims27
A photoacoustic imaging method, comprising:
- delivering diffuse light in transmission mode through a skull to one side of a region being imaged in a brain;
- using an ultrasonic transducer device to detect photoacoustic waves transmitted from an opposing side of the region, the photoacoustic waves received by the ultrasonic transducer device through an acoustic window in the skull, the photoacoustic waves generated based on the diffuse light delivered to the region;
- and
- reconstructing a plurality of photoacoustic images of the region based on the photoacoustic waves detected.
1 more element
A photoacoustic imaging method, comprising:
- obtaining photoacoustic data recorded by one or more data acquisition devices, wherein the photoacoustic data is based on photoacoustic signals of photoacoustic waves detected by an ultrasonic transducer device, the photoacoustic waves received through an acoustic window in a skull by the ultrasonic transducer device, the photoacoustic waves based on light delivered to a region being imaged in a brain, the light delivered to the brain in transmission mode through the skull to one side of the region in the brain, and the photoacoustic waves transmitted from an opposing side of the region;
- and
- reconstructing a plurality of photoacoustic images of the region based on the photoacoustic waves detected.
A photoacoustic imaging system, comprising:
- a light delivery module comprising a diffuser configured to diffuse a laser beam to produce diffuse light, the light delivery module configured to deliver the diffuse light in transmission mode through a skull to one side of a region being imaged in a brain;
- an acoustic detection module comprising an ultrasonic transducer device configured to detect photoacoustic waves transmitted from an opposing side of the region, the photoacoustic waves received by the ultrasonic transducer device through an acoustic window in the skull, the photoacoustic waves based on the diffuse light delivered to the region being imaged;
- and
- a data acquisition module comprising one or more data acquisition systems configured to receive acoustic signals from the acoustic detection module.
1 more element
Dependencies are inferred from the claim text.