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AssigneeCell Cure Neurosciences Ltd.
InventorsNir Netzer, Ofer Wiser, Bat Shahaf, Orit Gamburg, Lior Rosenberg Belmaker, Dana Hayoun Neeman, Osnat Bohana Kashtan
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Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries. A method of formulating human RPE cells for administration to a subject directly after thawing and of formulating RPE cell therapy compositions for cryopreservation and administration of the cryopreserved composition to a subject subsequent to thawing are also presented. In another aspect, the RTA composition may be formulated as a thaw and inject (TAI) composition, whereby the composition is administered by injection subsequent to thawing.
A method of treating a retinal degenerative disease in a human subject in need thereof, comprising thawing a frozen retinal pigment epithelium (RPE) cell therapy composition and administering the thawed RPE cell therapy composition to the retina of the subject directly after thawing without washing, reconstitution, or removal of dead cells;
Dependencies are inferred from the claim text.