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US 12,590,151 B2Granted
Anti-human CD19 antibodies with high affinity
AssigneeHoffmann-La Roche Inc.
InventorsThomas Hofer, Claudia Ferrara Koller, Ekkehard Moessner, Mi He
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Abstract
The present invention relates to antibodies against human CD19 (anti-human CD19 antibodies), methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same.
Claims25
An antibody that specifically binds to human CD19, wherein the antibody comprises
- (a) CDR-L1 comprising the amino acid sequence of SEQ ID NO:
- 43,
- (b) CDR-L2 comprising the amino acid sequence of SEQ ID NO:
- 44,
- (c) CDR-L3 comprising the amino acid sequence of SEQ ID NO:
- 45,
- (d) CDR-H1 comprising the amino acid sequence of SEQ ID NO:
- 46,
- (e) CDR-H2 comprising the amino acid sequence of SEQ ID NO:
- 47, and
- (f) CDR-H3 comprising the amino acid sequence of SEQ ID NO:
- 48.
9 more elements
Dependencies are inferred from the claim text.