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US 12,569,690 B2Granted
Cardiac contractility modulation for atrial arrhythmia patients
AssigneeImpulse Dynamics NV
InventorsDavid Prutchi, Simeon Ioannis Kedikoglou, Angela Connolly Stagg, Tamir Ben David
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Abstract
A cardiac treatment device, including: stimulation circuitry configured to generate a non-excitatory electrical signal which, when applied to ventricular tissue during a ventricular refractory period thereof improves a condition of heart failure in human patients; atrial arrhythmia detection circuitry; and decision circuitry which controls the stimulation circuitry to delivery said signal, also when said atrial arrhythmia detection circuitry detects an atrial arrhythmia.
Claims32
A cardiac treatment device, comprising:
- a stimulation circuitry configured to:
- generate a non-excitatory electrical signal, wherein when said signal is configured to be applied to a ventricular tissue during a ventricular refractory period it improves a condition of heart failure in human patients;
- an atrial arrhythmia detection circuitry;
- and
- a decision circuitry which controls the stimulation circuitry to deliver said signal during said ventricular refractory period, both when said atrial arrhythmia detection circuitry detects an atrial arrhythmia and when said atrial arrhythmia detection circuitry does not detect said atrial arrhythmia.
2 more elements
A cardiac treatment device, comprising:
- a stimulation circuitry configured to:
- generate a non-excitatory electrical signal, wherein when said signal is configured to be applied to a ventricular tissue during a ventricular refractory period it improves a condition of heart failure in human patients;
- an atrial arrhythmia detection circuitry;
- and
- a decision circuitry which controls the stimulation circuitry to deliver said signal during said ventricular refractory period regardless of detection of presence or absence of said atrial arrhythmia by said atrial arrhythmia detection circuitry.
2 more elements
A cardiac treatment device, comprising:
- a stimulation circuitry configured to:
- generate a non-excitatory electrical signal, wherein when said signal is configured to be applied to a ventricular tissue during a ventricular refractory period it improves a condition of heart failure in human patients;
- an atrial arrhythmia detection circuitry;
- a memory with a treatment protocol to deliver said non-excitatory electrical signal according to a schedule, and
- a decision circuitry which controls the stimulation circuitry to deliver said treatment during said ventricular refractory period, both when said atrial arrhythmia detection circuitry detects an atrial arrhythmia and when said atrial arrythmia detection circuitry does not detect said atrial arrhythmia.
2 more elements
A method of planning treatment for a patient, comprising:
- (a) identifying that a patient has an atrial arrhythmia or a risk to develop thereof;
- and
- (b) planning and implementing a treatment schedule for the patient with an implanted device that generates a non-excitatory electrical signal which, when applied to ventricular tissue during a ventricular refractory period thereof improves a condition of heart failure in human patients, wherein said non-excitatory electrical signal is applied both during an atrial arrhythmia event and in the absence of said atrial arrhythmia event.
A method of planning treatment for a patient, comprising:
- (a) identifying that a patient has an atrial arrhythmia or a risk to develop thereof;
- and
- (b) planning and implementing a treatment schedule for the patient with an implanted device that generates a non-excitatory electrical signal which, when applied to ventricular tissue during a ventricular refractory period thereof improves a condition of heart failure in human patients, wherein said non-excitatory electrical signal is applied regardless of detection of presence or absence of an event of said atrial arrhythmia.
A method of planning treatment for a patient, comprising:
- (a) identifying that a patient has an atrial arrhythmia or a risk to develop thereof;
- and
- (b) planning and implementing a treatment schedule for the patient with an implanted device that generates a non-excitatory electrical signal which, when applied to ventricular tissue during a ventricular refractory period thereof improves a condition of heart failure in human patients, wherein said treatment schedule is a prophylactic treatment according to a schedule, wherein said non-excitatory electrical signal is applied according to said prophylactic treatment schedule, wherein the non-excitatory electrical signal is applied both during an atrial arrhythmia event and in the absence of said atrial arrhythmia event.
Dependencies are inferred from the claim text.