Coating-securing agent
AssigneePublic University Corporation Yokohama City University
InventorsHideki Taniguchi, Soichiro Murata
Life of this patent
Estimating the term…
Abstract
Provided is a coating-fixing agent for transplanting a cell or a tissue onto the surface of an organ, intestinal membrane, peritoneal membrane, etc. Provided are: a formulation for coating and fixing a graft, the formulation comprising alginate; a formulation kit for coating and fixing a graft, comprising a formulation containing alginate and a divalent or higher valent metal salt in combination; and a method for transplanting a graft, comprising: transplanting the graft to a transplant site of a human or a non-human animal, and coating the graft with alginate.
Claims5
A method for transplanting a graft onto an organ surface, comprising:
- (a) detaching a membrane or layer covering the organ surface at a transplant site of a human or a non-human animal,
- (b) transplanting the graft to the transplant site on the organ surface of (a), wherein the graft contacts directly with the organ surface, and
- (c) coating the graft of (b) with a gel formed with alginate and a divalent or higher valent metal ion, thereby fixing the graft onto the transplant site after the graft has been transplanted onto the organ surface.
A method for transplanting a graft onto an organ surface, comprising:
- after transplanting the graft to a transplant site on an organ surface of a human or a non-human animal, adding dropwise to the graft an aqueous solution containing at least one selected from the group consisting of sodium alginate, potassium alginate and ammonium alginate, and further adding dropwise a divalent or higher valent metal ion to gelate the alginate for coating the graft, wherein the graft contacts directly the organ surface.
Dependencies are inferred from the claim text.