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US 12,492,222 B2Granted
Lipophilic enantiomers of desacetylglucosamine muramyl dipeptide with anti-inflammatory and growth promoting activity
AssigneeNutrivert LLC
InventorsHorace Disston Nalle, Jr., Bernhard Kaltenboeck
Life of this patent
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Abstract
Compositions of matter and methods to reduce inflammation in vertebrates and to promote growth and feed conversion in animals by administering an effective amount of a composition containing a mirror image molecule (enantiomer) of a lipophilic muramyl dipeptide (MDP) derivative that does not contain the N-acetylglucosamine moiety of MDP (i.e., a desmuramyl dipeptide).
Claims18
An oligopeptide of the following formula:
- or a pharmaceutically acceptable acid or salt thereof, wherein:
- R1 is C1-C18 linear alkyl or substituted or unsubstituted aryl;
- R2, R3, and R4 are each independently selected from H, substituted or unsubstituted alkyl and substituted or unsubstituted aryl;
- R5 is H, unsubstituted alkyl, or substituted or unsubstituted aryl;
- and
- X is O or NR6, wherein R6 is hydrogen, substituted or unsubstituted alkyl, or substituted or unsubstituted aryl.
3 more elements
Dependencies are inferred from the claim text.