Multimeric T-cell modulatory polypeptides and methods of use thereof
AssigneeCue Biopharma, Inc.
InventorsSaso Cemerski, Ronald D. Seidel, III, Rodolfo J. Chaparro, John F. Ross
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Abstract
The present disclosure provides T-cell modulatory multi-merit polypeptides that comprise an immunomodulatory polypeptide and that comprise an epitope-presenting Wilms tumor peptide. A T-cell modulatory multimeric polypeptide is useful for modulating the activity of a T cell, and for modulating an immune response in an individual.
Claims1
A composition comprising one or more nucleic acids, wherein the nucleic acids comprise nucleotide sequences encoding a first and second polypeptide, wherein the first polypeptide has the amino acid sequence set forth in SEQ ID NO:423 and the second polypeptide has the amino acid sequence set forth in SEQ ID NO:
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Dependencies are inferred from the claim text.