Use of glucocorticoids for the treatment of epithelial microbial infections of a fluid containing organ with a natural exterior orifice in mammals
AssigneeVirbac
InventorsBertrand Havrileck, Pierre Jasmin, David Mcgahie
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Abstract
The disclosure is directed to glucocorticoids for the treatment of epithelial microbial infections in fluid-containing organ having a natural exterior orifice in mammals; this new therapeutic use finds particular interest in the treatment of epithelial microbial infections of ear (such as otitis extema), udder (such as mastitis), and uterus (such as endometritis).
Claims7
A method for the treatment and/or the prevention of an epithelial microbial infection of the udder in a non-human mammal in need thereof, the method comprising topically administering in the udder to be treated an effective amount of hydrocortisone, a monoester, a diester or a salt thereof, wherein said epithelial microbial infection of the udder is mastitis, and
- wherein said hydrocortisone, monoester, diester or salt thereof is formulated in a pharmaceutical composition also comprising a pharmaceutically acceptable carrier, and wherein said composition does not contain any antibiotic agent, antifungal agent, antiviral agent or antimicrobial agent, wherein the quantity of hydrocortisone, monoester, diester or salt thereof in the composition to be applied in the udder is comprised between 1 and 50 mg and, wherein the composition is administered:
- (i) at least once a day for 1 to 10 days;
- or (ii) at least once a week.
Dependencies are inferred from the claim text.