US 12,344,906 B2Granted

System and method for reducing content of 5-hydroxymethylfurfural in high fructose corn syrup

AssigneeZhejiang Huakang Pharmaceutical Co., Ltd.

InventorsShengrong Chen, Jun Zhuge, Yuqing Cheng, Xinfeng Han, Jiaxing Luo

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Abstract

The present invention relates to a system for reducing a content of 5-hydroxymethylfurfural in a high fructose syrup, including an ion exchange positive column and an ion exchange negative column for performing cation and anion removals in sequence for an F42 high fructose syrup obtained by performing isomerization and first decolorization, a heat exchanger for performing heat exchange and temperature reduction for an F55 high fructose syrup obtained by performing concentration, chromatographic separation, blending and second decolorization in sequence for the F42 high fructose syrup subjected to ion exchange, a mixed bed column for performing purification for the heat-exchanged F55 high fructose syrup, and an evaporation tank for performing concentration for the F55 high fructose syrup subjected to mixed bed treatment. The present invention further provides a method of reducing a content of 5-hydroxymethylfurfural in a high fructose syrup. In the present invention, optimization is performed for ion exchange and operation modes and parameters of the mixed bed such that the HMF content in the high fructose syrup product is reduced in a case of ensuring the quality of the high fructose syrup product, thus improving the quality of the high fructose syrup product.

Claims9

Dependent claims

A system for reducing a content of 5-hydroxymethylfurfural in a high fructose syrup, comprising:

an ion exchange positive column and an ion exchange negative column for removing cations and anions from an F42 high fructose syrup;
a heat exchanger unit for reducing the temperature of an F55 high fructose syrup obtained from the F42 high fructose syrup to obtain a heat-exchanged F55 high fructose syrup;
a mixed bed column for purifying the heat-exchanged F55 high fructose syrup to obtain a purified F55 high fructose syrup;
and
an evaporation tank for concentrating the purified F55 high fructose syrup,
wherein the heat exchanger unit comprises a first heat exchanger and a second heat exchanger connected in series,
the first heat exchanger comprises a first inlet, a second inlet, a first outlet, and a second outlet,
the second heat exchanger comprises a first inlet, a second inlet, a first outlet, and a second outlet,
the heat exchanger unit is configured to allow the F55 high fructose syrup to enter the first heat exchanger through the first inlet of the first heat exchanger, exit the first outlet of the first heat exchanger, enter the second heat exchanger through the first inlet of the second heat exchanger, exit the first outlet of the second heat exchanger, and enter a liquid inlet of the mixed bed column through a liquid inlet pipe, and
the heat exchanger unit is further configured to allow the F55 high fructose syrup purified by the mixed bed column to enter the second inlet of the first heat exchanger through an outlet of the mixed bed column, exit the second outlet of the first heat exchanger, and enter a liquid inlet of the evaporation tank,
wherein the second inlet of the second heat exchanger is in communication with cooling water through a water inlet pipe, and the second heat exchanger is configured to allow the heat-exchanged cooling water to exit the second outlet of the second heat exchanger.

8 more elements

A method of reducing a content of 5-hydroxymethylfurfural in a high fructose syrup, comprising the following steps:

at step 1, obtaining a glucose syrup by subjecting starch to liquefaction, saccharification and refining;
at step 2, mixing the glucose syrup in step 1 with a raffinate in step 6 and concentrating the mixture to obtain a glucose syrup solution;
at step 3, bringing the glucose syrup solution in step 2 into an isomerization column to obtain an F42 high fructose syrup;
at step 4, decolorizing the F42 high fructose syrup in step 3 and then bringing the F42 high fructose syrup into an ion exchange positive column and an ion exchange negative column in sequence to remove cations and anions so as to obtain a refined F42 high fructose syrup;
at step 5, concentrating the refined F42 high fructose syrup in step 4 to obtain a finished F42 high fructose syrup;
at step 6, bringing about 42-50% of the finished F42 high fructose syrup in step 5 into chromatographic separation to obtain an F90 high fructose syrup extract liquid and a raffinate, wherein the raffinate is reused in step 2;
at step 7, blending the F90 high fructose syrup extract liquid in step 6 with a part of the finished F42 high fructose syrup in step 5 to obtain an F55 high fructose syrup;
at step 8, decolorizing the F55 high fructose syrup in step 7 and then bringing the F55 high fructose syrup into a mixed bed column so as to obtain a refined F55 high fructose syrup;
wherein, in order to increase a feed temperature, the F55 high fructose syrup is subject to heat exchange with a discharge of the mixed bed column and heat exchange with cooling water to obtain a heat-exchanged F55 high fructose syrup before the F55 high fructose syrup enters the mixed bed column;
at step 9, concentrating the refined F55 high fructose syrup in step 8 by evaporation to obtain a finished F55 high fructose syrup.

7 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/775,002Filed 7 Feb 2021
Priority: CN 202010087317.911 Feb 2020
Published: US 2022/0389526 A18 Dec 2022
Granted: 1 Jul 2025
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C13K 1/08
Obtained by saccharification of starch or raw materials containing starch: purifying
B01J 47/026
Column or bed processes: using columns or beds of different ion exchange materials in series
B01J 47/028
Using columns or beds of different ion exchange materials in series: with alternately arranged cationic and anionic exchangers
B01J 47/04
Column or bed processes: mixed-bed processes