Contrast enhancement method for the objects with intrinsic partial volume effect

A system for contrast enhancement, the system comprising:

• a processor configured to:
• determine a target region of a subject being imaged;
• estimate an achievable spatial resolution;
• and
• select an increased spatial resolution that is greater than a predetermined spatial resolution and equal to or less than the achievable spatial resolution;
• and
• a receiver configured to acquire image data of the target region with the increased spatial resolution, wherein a voxel or a pixel of the image data corresponding to a region of interest in the target region includes intrinsic partial volume effect and another voxel or pixel of the image data corresponding to a boundary of the region of interest in the target region includes extrinsic partial volume effect,
• wherein a contrast between the region of interest and other tissue region in the image data acquired with the increased spatial resolution is greater than a contrast between the region of interest and other tissue region in image data acquired with the predetermined spatial resolution due to the intrinsic partial volume effect.