Processing system for processing specimens using acoustic energy
AssigneeVentana Medical Systems, Inc.
InventorsDavid Chafin, Michael Otter, Abbey Pierson, Jefferson Curtis Taft
Life of this patent
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Abstract
A method for fixing a biological sample includes delivering energy through a biological sample that has been removed from a subject, while fixing the biological sample. A change in speed of the energy traveling through the biological sample is evaluated to monitor the progress of the fixation. A system for performing the method can include a transmitter that outputs the energy and a receiver configured to detect the transmitted energy. A computing device can evaluate the speed of the energy based on signals from the receiver.
Claims15
A method of processing a tissue sample comprising:
- (i) immersing the tissue sample in a fixative solution having a first temperature ranging from 0° C. to 10° C. for a first time period sufficient to diffuse the fixative solution into an interior region of the tissue sample without substantially forming cross-links within the tissue sample;
- and
- (ii) continuing immersion of the tissue sample in the fixative solution for a second period of time sufficient to cause cross-linking within the tissue sample,
- wherein the tissue sample is not exposed to ultrasonic or electromagnetic irradiation during either (i) the immersion of the tissue sample in the fixative solution, or (ii) the continuing immersion of the tissue sample in the fixative solution.
Dependencies are inferred from the claim text.