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AssigneeTongji Hospital, Tongji Medical College of Hust
InventorsCongyi Wang, Shanjie Rong, Fei Sun, Chunliang Yang, Jiahui Luo
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The present disclosure relates to the technical field of chemoimmunology, and in particular to an anti-receptor expressed on lymphoid tissues (RELT) recombinant monoclonal antibody and a preparation method and use thereof. The anti-RELT recombinant monoclonal antibody includes a heavy chain variable region and a light chain variable region, where the amino acid sequence of the heavy chain variable region is set forth in SEQ ID NO: 4; the amino acid sequence of the light chain variable region is set forth in SEQ ID NO: 5; and the anti-RELT recombinant monoclonal antibody has a biological activity of neutralizing a function of RELT. In addition, because the anti-RELT recombinant monoclonal antibody has the biological activity of neutralizing the function of RELT, the anti-RELT recombinant monoclonal antibody can specifically recognize and detect the expression of RELT in different tissues and cells.
An anti-receptor expressed on lymphoid tissues (RELT) recombinant monoclonal antibody, comprising a heavy chain variable region and a light chain variable region, wherein the amino acid sequence of the heavy chain variable region is set forth in SEQ ID NO:
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