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US 12,215,136 B2Granted
Exosome for stimulating T cell and pharmaceutical use thereof
AssigneeThe Catholic University of Korea Industry-Academic Cooperation Foundation
InventorsTai Gyu Kim, Hyun Jung Sohn, Su Eon Kim
Life of this patent
Estimating the term…
Abstract
The present invention relates to an exosome for stimulating T cells and the pharmaceutical use thereof. Immune exosomes secreted from artificial antigen-presenting cells which express HLA, CD32, and co-stimulatory molecules CD32, CD80, CD83, and 4-1BBL are used to stimulate naive CD8+ T cells whereby preventive and therapeutic effects on tumors, pathogen infections, or autoimmune diseases can be provided.
Claims10
An exosome which expresses a human leukocyte antigen (HLA), CD32, CD80, CD83, and 4-1BBL.
Dependencies are inferred from the claim text.