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US 12,215,112 B2Granted
CD151 inhibitors
AssigneeEsfam Biotech Pty Ltd
InventorsJohn Thomas Feutrill, Jean-Marc Garnier, Albert George Frauman
Life of this patent
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Abstract
The present invention relates to compounds of formula (I) that have the ability to inhibit CD151.
Claims19
A compound of Formula (I):
- Formula (I)
- wherein
- R1, R2, and R3 are each independently selected from the group consisting of H and C1-C12alkyl,
- R4 is selected from the group consisting of H and C1-C12alkyl,
- R5 is selected from the group consisting of H, optionally substituted C6-C18aryl, optionally substituted C1-C18heteroaryl, optionally substituted C6-C18arylC1-C12alkyl-, and optionally substituted C1-C18heteroarylC1-C12alkyl-;
- R6 is selected from the group consisting of H, C1-C12alkyl, C3-C6 cycloalkyl, and C1-C5 heterocycloalkyl,
- R7 is selected from the group consisting of H and C1-C12alkyl;
- R8 is selected from the group consisting of H, C1-C12alkyl, optionally substituted C6-C18aryl, optionally substituted C1-C18heteroaryl, optionally substituted C6-C18arylC1-C12alkyl-, and optionally substituted C1-C18heteroarylC1-C12alkyl-;
- or R7 and R8 when taken together with the nitrogen atom to which they are attached form an optionally substituted C2-C12heterocyclic group;
- or a pharmaceutically acceptable salt thereof.
7 more elements
Dependencies are inferred from the claim text.