Nicotinamide dummy template surface molecularly imprinted polymer and preparation method and application thereof

A method of using a nicotinamide dummy template surface molecularly imprinted polymer (DMIP), comprising preparing the DMIP, and adding the DMIP in a tea extract aqueous solution and removing imidacloprid and acetamiprid from the tea extract aqueous solution, wherein a preparation method of the nicotinamide dummy template surface molecularly imprinted polymer comprises the following steps:

• A1. preparation of a modified silica gel carrier
• soaking granular silica gel in hydrochloric acid for treatment, filtering and washing the silica gel to neutral and drying the silica gel;
• in g/mL, mixing the dried silica gel with toluene in a mass-volume ratio of 1:40-1:8;
• adding 3-aminopropyltriethoxysilane (APTS) and pyridine dropwise, and at a reaction temperature of 363-383 K in a nitrogen atmosphere, performing refluxing for 20-30 h;
• after washing the obtained mixture with toluene, acetone, ether and methanol, performing vacuum drying to prepare amino-modified silica gel;
• in g/mL, mixing the amino-modified silica gel with toluene in a mass-volume ratio of 1:40-1:8;
• adding acryloyl chloride in a nitrogen atmosphere, adding triethylamine dropwise after magnetic stirring, and performing stirring at room temperature for reacting for 20-30 h;
• and after washing the obtained mixture with toluene, acetone, ether and methanol, performing vacuum drying to prepare acyl-modified silica gel;
• and
• A2. preparation of a dummy template surface molecularly imprinted polymer in g/mL, dissolving nicotinamide in a methanol aqueous solution at a mass-volume ratio of 1:1-3:1;
• adding the acyl-modified silica gel and methacrylic acid (MAA), and after ultrasonic dispersion, reacting for 2-6 h in the dark, wherein a mass ratio of the nicotinamide to the acyl-modified silica gel is 5:6-5:3;
• after the reaction, adding ethylene glycol dimethacrylate (EGDMA) and azobisisobutyronitrile (AIBN) in a nitrogen atmosphere, and performing sealed reaction at 323-343 K in a water bath for 20-28 h;
• and removing a template by Soxhlet extraction, and performing washing and drying to prepare the dummy template surface molecularly imprinted polymer.