Applicator system containing a microneedle array which comprises an active ingredient for wound healing
AssigneeLTS Lohmann Therapie-Systeme AG
InventorsStefan Henke, Karsten Heuser
Life of this patent
Estimating the term…
Abstract
The invention relates to an applicator system comprising a microneedle array and to the use thereof for the intradermal delivery of active ingredients, and in particular of medicinal drugs, wherein this microneedle array is suitable for penetrating the skin of humans or animals and includes at least one active ingredient for wound healing.
Claims12
An applicator system comprising a microneedle array for use for the intradermal delivery of a first active ingredient, the applicator system comprising:
- a plurality of microneedles on a carrier, wherein the microneedles are made of a polymer matrix in which at least one second active ingredient for wound healing is integrated or incorporated;
- a trigger mechanism;
- and
- at least one reservoir for storing the first active ingredient, the reservoir being in connection to the microneedles;
- and
- wherein the first active ingredient is different from the at least one second active ingredient for wound healing, and the first active ingredient is a medicinal drug;
- wherein the at least one second active ingredient for wound healing is selected from the group consisting of dexpanthenol, collagen, hyaluronic acid, and combinations thereof;
- and
- wherein the polymer of the polymer matrix is selected from the group consisting of polylactides, polyglycolides, polylactide-co-glycolides, polyanhydrides, poly(ortho)esters, polyurethanes, polybutyric acids, polyvaleric acids, polylactide-co-caprolactones, polycarbonates, polyesters, polyvinyl chloride, polyacrylamides, cycloolefin (co)polymers, polymethacrylates, and thermoplastics.
An applicator system comprising a microneedle array for the intradermal delivery of a first active ingredient, the applicator system comprising:
- a plurality of microneedles on a carrier, wherein the microneedles are made of a polymer matrix in which at least one second active ingredient for wound healing is integrated or incorporated;
- a trigger mechanism;
- and
- at least one reservoir in connection with the microneedles;
- and
- wherein the at least one reservoir contains the first active ingredient;
- wherein the first active ingredient is different from the at least one second active ingredient for wound healing, and the first active ingredient is a medicinal drug;
- wherein the at least one second active ingredient for wound healing is selected from the group consisting of dexpanthenol, collagen, hyaluronic acid, and combinations thereof;
- and
- wherein the polymer of the polymer matrix is selected from the group consisting of polylactides, polyglycolides, polylactide-co-glycolides, polyanhydrides, poly(ortho)esters, polyurethanes, polybutyric acids, polyvaleric acids, polylactide-co-caprolactones, polycarbonates, polyesters, polyvinyl chloride, polyacrylamides, cycloolefin (co)polymers, polymethacrylates, and thermoplastics.
Dependencies are inferred from the claim text.